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Alex Vieira



  • Higher Ed: Science 


Alexandre R. Vieira

Born in Rio de Janeiro, Brazil, Dr. Alex Vieira took a route north that brought him to the University of Pittsburgh after stopping at the University of Iowa for almost six years for a post-doctoral training in human molecular genetics. It was in Iowa City, under the guidance of Dr. Jeffrey Murray that Alex learned how to design and execute human genetics studies. Dr. Vieira received his DDS from the Federal University of Rio de Janeiro, where he also did his training in Pediatric Dentistry and received a master's degree that was followed by a PhD in Genetics.
Having great expertise in the area of genetics and clefting, Dr. Vieira is currently an assistant professor in the Department of Oral Biology, at the School of Dental Medicine at the University of Pittsburgh and has secondary appointments at the Department of Pediatric Dentistry at the School of Dental Medicine, and at the Department of Human Genetics at the Graduate College of Public Health. At the School of Dental Medicine, he also is the director of Clinical Research and is the founder and director of the Dental Registry and DNA Repository, the only project in the world to keep DNA samples linked to a comprehensive set of dental clinical information.
Dr. Vieira also worked in the Latin American Birth Defects Registry ECLAMC, and pioneered the collection of biological samples in that multi--country study in 1997. Currently, he combines his background in pediatric dentistry and genetics to develop a research program that aims to provide a better understanding of common dental traits of complex etiology. 


pediatric dentistry
cleft lip and palate 


91. Weinberg SM, Brandon CA, McHenry TH, Neiswanger K, Deleyiannis FWB, de Salamanca JE, Castilla EE, Czeizel AE, Vieira AR, Marazita ML. Rethinking isolated cleft palate: evidence of occult lip defects in a subset of cases. Am J Med Genet A (In Press)
90. Vieira AR, Goldstein McHenry T, Daack-Hirsch S, Murray JC, Marazita ML. A Genome Wide Linkage Scan for Cleft Lip and Palate and Dental Anomalies. Am J Med Genet A (In Press).
89. Vieira AR, Howe A, Murray JC. Studies of -Aminobutyric Acid Type A Receptor b3 (GABRB3) and Glutamic Acid Decarboxylase 67 (GAD67) with Oral Clefts. Am J Med Genet A (In Press).
88. Kchler EC, Risso PA, Costa MC, Modesto A, Vieira AR. Assessing the proposed association between tooth agenesis and taurodontism in 975 pediatric subjects. Int J Paediatr Dent (In Press).
87. Oakley M, Vieira AR. The endangered clinical teacher scholar: will this eliminate discovery from the dental school environment? J Dent Res 2008; 87:200-202.
86. Vieira AR. Unraveling human cleft lip and palate research. J Dent Res 2008; 87:119-125.
85. Rose EK, Vieira AR. Caries and periodontal disease: Insights from two US populations living a century apart. Oral Health Prev Dentistry 2008; 6:23-28.
84. Deeley K, Letra A, Rose EK, Brandon CA, Resick JM, Marazita ML, Vieira AR. Possible association of amelogenin to high caries experience in a Guatemalan-Mayan population. Caries Res 2008; 42:8-13.
83. Carvalho FM, Vieira AR, Tinoco EMB. Genetics of aggressive periodontitis in Brazilians: Preliminary data in African-Brazilian families. Rev Periodontia 2007; 17: 35-40.
82. Letra A, Menezes R, Granjeiro JM, Vieira AR. Defining cleft subphenotypes based on dental development. J Dent Res 2007; 86:986-991.
81. Vieira AR, Cooper ME, Marazita ML, Orioli IM, Castilla EE. Interferon regulatory factor 6 (IRF6) is associated with oral-facial cleft in individuals that originate in South America. Am J Med Genet A 2007; 143:2075-2078.
80. Riley BM, Schultz RE, Cooper ME, Goldstein-McHenry T, Daack-Hirsch S, Lee KT, Dragan E, Vieira AR, Lidral AC, Marazita ML, Murray JC. A genome-wide linkage scan for cleft lip and palate identifies a novel locus on 8p11-23. Am J Med Genet A 2007; 143:846-852.
79. Riley BM, Mansilla MA, Ma J, Daack-Hirsch S, Maher BS, Raffensperger LM, Russo ET, Vieira AR, Dode C, Mohammadi M, Marazita ML, Murray JC. Impaired FGF signaling contributes to cleft lip and palate. Proc Natl Acad Sci USA 2007; 104:4512-4517.
78. Vieira, AR, Modesto A, Meira R, Barbosa ARS, Lidral AC, Murray JC. Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis. Am J Med Genet A 2007; 143:538-545.