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Jeremy Thorner

PROJECT AFFILIATION:

PROFESSIONAL ROLES

  • Higher Ed: Science 

BIO

Jeremy W. Thorner was born and raised in Quincy, MA. He received his A.B., magna cum laude, in Biochemical Sciences from Harvard College in 1967, and his Ph.D. in Biochemistry from Harvard University in 1972. He then conducted postdoctoral research in the Dept. of Biochemistry at Stanford University School of Medicine from 1972 to 1974. He commenced his faculty position at the University of California at Berkeley in 1974, and has been there ever since. He currently holds the William V. Power Endowed Chair in Biology and is a Professor in the Division of Biochemistry and Molecular Biology (BMB) of the Department of Molecular and Cell Biology (MCB) at the University of California at Berkeley. Over the years, he has received many honors for the quality of his research and teaching, including a ten-year MERIT Award from the National Institute of General Medical Sciences (1989-1998) and the Dean's Award for Distinguished Research Mentoring of Undergraduates in the Biological Sciences from the College of Letters and Science at Berkeley (2004), as well as other accolades for his accomplishments, including election as a Fellow of the American Association for the Advancement of Science (1998), as a Fellow of the American Academy of Microbiology (1998), and as a Member of the American Academy of Arts and Sciences (2007). 

EXPERTISE

Prof. Thorner's research interests include the structure and function of peptide ligands, receptors, and other components of the signal transduction machinery of eukaryotic cells, in particular in Saccharomyces cerevisiae (baker's yeast). His work has included investigation of kinases, phosphatases, G-proteins, G-protein-coupled receptors, and the processing and transport of peptide hormones. 

RECENT PUBLICATIONS

Roelants FM, Baltz AG, Trott AE, Fereres S, Thorner J (2009) A novel protein kinase network that regulates the function of aminophospholipid flippases. Proc. Natl. Acad. Sci. USA [Epub, 4 Dec 09]

McMurray MA, Thorner J (2009) Septins: molecular partitioning and the generation of cellular asymmetry. Cell Div. 4: 18.1-18.40.

Rockwell NC, Wolfger H, Kuchler K, Thorner J (2009) ABC transporter Pdr10 regulates the membrane microenvironment of Pdr12 in Saccharomyces cerevisiae. J. Membr. Biol. 229: 27-52.

McMurray MA, Thorner J (2009) Reuse, replace, recycle: specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast. Cell Cycle 8: 195-203.

Garrenton LS, Braunwarth A, Irniger S, Hurt E, Knzler M, Thorner J (2009) Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence. Mol. Cell. Biol. 29: 582-601.

Westfall PJ, Patterson JC, Chen RE, Thorner J (2008) Stress resistance and signal fidelity independent of nuclear MAPK function. Proc. Natl. Acad. Sci. USA 105: 12212-12217

McMurray MA, Thorner J (2008) Septin stability and recycling during dynamic structural transitions in cell division and development. Curr Biol. 18: 1203-1208.

Bertin A, McMurray MA, Grob P, Park SS, Garcia G 3rd, Patanwala I, Ng HL, Alber T, Thorner J, Nogales E (2008) Saccharomyces cerevisiae septins: supramolecular organization of hetero-oligomers and the mechanism of filament assembly. Proc. Natl. Acad. Sci. USA 105: 8274-8279.