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Daniel Brazeau

PROJECT AFFILIATION:

PROFESSIONAL ROLES

  • Higher Ed: Science 

BIO

Daniel Brazeau is the Director of the Pharmaceutical Genetics Laboratory (PGL) in the School of Pharmacy and Pharmaceutical Sciences and a Research Associate Professor in the Department of Pharmaceutical Sciences. He received his B.S. and M.S. in Biology from the University of Toledo and earned his Ph.D. in Biological Sciences (1989) from the University at Buffalo. After completing postdoctoral training in population genetics at the University of Houston he was a research assistant professor in the Department of Zoology at the University of Florida and Director of the University of Florida's Genetic Analysis Laboratory in the Interdisciplinary Research Center for Biotechnology. The primary role of the PGL is to provide extensive training and research support for a wide array of molecular genetic techniques to assist researchers in addressing a broad range of questions including population genetics, gene expression, bioinformatics, genotyping and molecular genetics. Presently at the University at Buffalo the PG L has 19 projects ongoing involving 15 principle investigators, 18 graduate students, 8 Pharm. D. students, and 7 undergraduates across 10 departments and 4 universities. In addition the PGL provides extensive education and training to not only university personnel but also to outside researchers and professionals through a series of workshops and short courses in Molecular techniques including DNA microarrays, siRNA, quantitative real-time PCR, statistical packages/programs for genetic analysis, microsatellite development and analysis, and molecular genetic methodologies. Dr Brazeau's research interests involve the areas of population molecular genetics and pharmcogenomic studies. He teaches courses in molecular genetic methodologies and pharmacogenomics for graduate and professional students. 

EXPERTISE

Pharmacogenomics
Pharmacogenetics
Population Genetics 

RECENT PUBLICATIONS

1. Atchison, A. Sammarco, P. and Brazeau D.A. 2008. Genetic Connectivity in Corals on the Flower Garden Banks and Surrounding Oil/Gas Platforms, Gulf of Mexico. J Exp Mar Biol Ecol 365:1-12
2. Sara E. Renzi, Mark M. Sauberan, Daniel A. Brazeau, and Gayle A. Brazeau, 2009. Relationship Between Student Leadership Activities and Prepharmacy Years in College. AM J Pharmaceutical Ed 72(6) Article 149
3. Urvi Telang, Daniel A. Brazeau, and Marilyn E. Morris. 2009. Comparison of the Effects of Phenethyl Isothiocyanate and Sulforaphane on Gene Expression in Breast Cancer and Normal Mammary Epithelial Cells Experimental Biology and Medicine 234 (3)287-295
4. Chanda, P., L. Sucheston, A. Zhang, D. Brazeau, J. L. Freudenheim, C. Ambrosone, and M. Ramanathan. 2008. AMBIENCE: a novel approach and efficient algorithm for identifying informative genetic and environmental associations with complex phenotypes. Genetics 180:1191-1210.
5. Brazeau, D.A. and G.A. Brazeau 2008. Pharmacogenomics of Warfarin Therapy for venous thromboembolism. Clinical Laboratory No. CL-8:2-5.
6. Tsai, W. J., K. M. McCormick, D. A. Brazeau, and G. A. Brazeau. 2007. Estrogen effects on skeletal muscle insulin-like growth factor 1 and myostatin in ovariectomized rats. Exp Biol Med (Maywood) 232:1314-1325.
7. Chanda, P., A. Zhang, D. Brazeau, L. Sucheston, J. L. Freudenheim, C. Ambrosone, and M. Ramanathan. 2007. Information-theoretic metrics for visualizing gene-environment interactions. Am J Hum Genet 81:939-963.
8. Ma, Q., Brazeau DA. Forrest, A. and Morse GD. 2007. Advances in pharmacogenomics of antiretrovirals: an update. Pharmacogenomics 8:1169-1178.
9. Moon, Y.J, Brazeau, D., Morris, M. 2007. Effects of flavonoida s Geniatein and Biochanin A on gene expression and their metabolism in human mammary cells. Nutrition and Cancer 57:48-58.
10. Moon, Y. J., S. Zhang, D. A. Brazeau, and M. E. Morris. 2007. Effects of the flavonoid biochanin A on gene expression in primary human hepatocytes and human intestinal cells. Mol Nutr Food Res 51:317-323.